Pretreatment with a very low dose of intravenous esmolol reduces propofol injection pain.

Sat, 28 Mar 2026 13:06:29 +0300

Objective: Propofol causes considerable pain on injection, although different methods and propofol formulations have been used to decrease it. We aimed to investigate the effect of i.v esmolol pretreatment on the propofol injection pain.
Methods: Ninety ASA I-II patients undergoing elective surgery under general anesthesia were randomly assigned into three groups, tirthy each. A 20 G cannula wa...