Ömer Faruk Elmas1, Mahmut Sami Metin1, Okan Kızılyel1, Akın Aktaş2, Canan Birdal1

1Ataturk University, Faculty Of Medicine, Dermatology Department, Erzurum
2Ataturk University, Faculty Of Medicine, Internal Medicine Department, Erzurum

Keywords: Capecitabine, hand-foot syndrome, palmoplantar dysesthesia

Abstract

Palmoplantar dysesthesia is a dermatological toxic reaction caused by chemotherapeutics. It is also known as hand-foot syndrome syndrome. It is not a life threatening condition but it decreases life quality of patients. Clinically, dysesthesia, erythema, edema and desquamation on palmoplantar region are seen in patients. Cytarabine, doxorubicine, capecitabine, epirubicine, docetaxel, vinorelbine and 5-FU are chemotherapeutics that may cause palmoplantar dysesthesia syndrome. Our case was 62 years old woman presented with diffused erythema on palmoplantar area after usage of capecitabine for metastatic meme carcinoma. We reported this case because palmoplantar dysesthesia syndrome caused by capecitabine may affect treatment compliance of patients.