İpek Erdoğan1, Türkay Çakan1, Ayşe Özcan1, Esra Türkyılmaz1, Bülent Baltacı1, Bayazit Dikmen2

1Department Of Anesthesiology And Reanimation, Ankara Training And Research Hospital, Ministry Of Health, Ankara, Turkey
2* Department Of Anesthesiology And Reanimation, Ankara Numune Training And Research Hospital, Ministry Of Health, Ankara, Turkey

Keywords: Postoperative analgesia, nonsteroidal-antiinflammatory drugs, lornoxicam, myomectomy

Abstract

BACKGROUND: In this prospective, randomized study, we evaluate the postoperative analgesic effect of lornoxicam after myomectomy operations. MATERIAL-METHOD: Forty ASA I-II patients scheduled for myomectomy operation were enrolled to this study. Patients were randomly divided into two groups and epidural block was performed with 0,75 % ropivacaine. After the operation, morphine Patient Controlled Epidural Analgesia (PCEA) combined with placebo (saline 2 ml iv) and morphine PCEA combined with lornoxicam 8 mg iv were administered to patients in Group I and Group II, respectively. Pain was assessed at the 0,1st, 2nd, 4th, 6th, 8th, 12th and 24th hours postoperatively. Chi-square and student’s t tests were used for statistical analysis.
RESULTS: VAS( Visual Analog Scale) scores were higher in Group I than Group II at 2nd, 4th, 6th and 24th hours. Total morphine consumption was 10.45± 4.03 in Group I and 4.25 ± 1.74 in Group II. CONCLUSION: Single dose iv lornoxicam is a safe and an effective treatment option of post-myomectomy pain as it produces effective analgesia, reduces morphine consumption and does not increase the side effects.