Sercan Bulut Çelik1, Hüseyin Can2, Melih Kaan Sözmen3, Tijen Şengezer4, Yusuf Cem Kaplan5, Gökçenur Utlu2, Alp Şener2, Arzu Aybek Yılmaz2, Olgu Aygün6

1Family Health Center Number 11, Batman, Turkey
2Department of Family Medicine, Katip Çelebi University Faculty of Medicine, İzmir, Turkey
3Department of Public Health, Katip Çelebi University Faculty of Medicine, İzmir, Turkey
4Department of Family Medicine, Numune Training and Research Hospital, Ankara, Turkey
5Department of Pharmacology, Katip Çelebi University Faculty of Medicine, İzmir
6Karabağlar Community Health Center, İzmir, Turkey

Keywords: Addiction, cigarette, neuropathy, pain.

Abstract

Objectives: Nicotine addiction is one of the most important causes of the general failure of treatment and keeping the habit of smoking. Peripheral neuropathy is a leading factor of smoking. This study aimed to analyze the association of neuropathic pain and addiction levels of individuals.
Methods: The study was performed on the day on which the smokers visited the hospital for any reason. The Douleur Neuropathique 4 (DN-4) Scale and Fagerström Addiction Survey were administered to the individuals after obtaining their consent.
Results: In total, 444 individuals were included in the study, and 57.2% of them were males (n = 254). The age average of the individuals with neuropathic pain (46.4±12.3 years) was significantly higher than that of those without pain. The individuals with pain smoked approximately 31.8±18.3 packet/year cigarettes, whereas those without pain smoked approximately 22.4 ± 15.5 packet/year cigarettes; the difference was significant statistically (p<0.05). According to multivariate logistic regression analysis with the backward elimination method, the existence of pain was found to be PR = 2.22 (95% GA, 1.26–3.91) in terms of sex, DM existence was found to be PR = 1.97 (95% GA, 1.02–3.81), and for each standard deviation increase (2.7) in Fagerström scale, PR was 1.29 (95% GA, 1.14–1.46).
Conclusion: Smoking is a risk factor for neuropathic pain. In our study, the possibility of neuropathic pain increases as the duration of smoking and addiction level increase, and with diabetes, this rate increases even more. It is extremely important that the smokers should be informed regarding these facts and possibilities.