The efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia technique in post-laparoscopic cholecystectomy pain treatment
Perihan Ekmekçi1, Züleyha Kazak Bengisun1, Baturay Kansu Kazbek1, Salih Erpulat Öziş2, Huri Taştan1, Arif Hikmet Süer1
1Ufuk University Faculty Of Medicine Dr. Rıdvan Ege Hospital Department Of Anesthesiology And Reanimation Ankara
2Ufuk University Faculty Of Medicine Dr. Rıdvan Ege Hospital Department Of General Surgery Ankara
Keywords: Laparoscopic Cholecystectomy, Postoperative Pain, Dexketoprofen Trometamol, Patient Controlled Analgesia
Abstract
Purpose: Pain treatment in laparoscopic cholecystectomy, which is performed in increasing numbers as an ambulatory procedure, is an important issue.Although laparoscopic cholecystectomy is regarded as an ambulatory procedure, patients are often hospitalized due to pain and this increases opioid consumption and side effects caused by opioids. This study aims at evaluating the efficacy of adding dexketoprofen trometamol to tramadol with patient controlled analgesia in post-laparoscopic cholecystectomy pain treatment.
Method: 40 patients in ASA I-II risk groups aged between 18-65 years were enrolled in the study and were randomized using closed envelope method. In Group TD 600 mg tramadol and 100 mg dexketoprofen trometamol, in Group T 600 mg tramadol was added to 100 ml 0.9% normal saline for PCA. 8 mg lornoxicam iv was given if VAS >40 in the postoperative period.
Results: There was no statistically significant difference in terms of adverse effects (hypotension, bradycardia, sedation) but in Group T 4 patients complained of nausea and 3 complained of vomiting. Opioid consumption was lower and patient satisfaction was higher in group TD.
Conclusion: This study has shown that adding dexketoprofen trometamol to tramadol in patient controlled analgesia following laparoscopic cholecystectomy lowers VAS scores, increases patient satisfaction and decreases opioid consumption.