Prevalence of patent foramen ovale in patients with migraine
Aslı Demirtaş Tatlıdede1, Buket Oflazoğlu1, Seden Erten Çelik2, Ülker Anadol1, Hulki Forta2
1Şişli Etfal Training And Research Hospital, Neurology Clinic, İstanbul
2Siyami Ersek Thoracic And Cardiovascular Surgery Training And Research Hospital, Cardiology Clinic, İstanbul
Keywords: Migraine, Echocardiography, Patent foremen ovale
Abstract
Recent evidence supports that the prevalence of patent foramen ovale is higher in patients with migraine with aura. We conducted a case-control study and searched for intra-atrial right to left shunt in 53 patients with migraine. PFO was detected by means of transthoracic echocardiography with administration of contrast medium during valsalva maneuver and the results were compared with age and sex matched 27 healthy controls. Patent foramen ovale was more frequent in the migraine group (p<.01). The percentages of PFO in migraine patients with aura, without aura and the control group were 66.7 %, 47.4 % and 22.2 %, respectively. Our results are supportive of an association between PFO and migraine, especially with aura.