Prilocaine and prilocaine - meperidine combination in regional intravenous anesthesia
S. Tuncer1, H. Barışkaner2, L. Pirbudak3, Ş. Otelcioğlu4
1Selçuk Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon A.B.D., Yrd. Doç. Dr.
2Selçuk Üniversitesi Tıp Fakültesi, Farmakoloji A.B.D., Yrd. Doç. Dr.
3Selçuk Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon A.B.D., Uzm. Dr
4Selçuk Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon A.B.D., Prof. Dr.
Keywords: Prilocaine, prilocaine - meperidine combination, regional intravenous anesthesia
Abstract
In this study we aimed to assess the effects and side effects of prilocaine and meperidine added to decreased dose and concentration of prilocaine, in sensorial and motor block during regional anesthesia. Thirty ASA I-II patients, undergoing upper extremity operation were studied and randomly divided into two groups. First group recieved 1 % prilocaine while the second recieved 0.5 % prilocaine + 1 mg/kg meperidine in 40 ml of distilled water in 90 seconds in accordance with the RIVA technique. Statistical analysis was done with Mann Whitney-U test and p<0.05 was accepted statistically significant. In conclusion we observed that analgesia and motor block beginning times were shorter and postoperative pain was less in the second group. Thus we think that the combination of meperidine with low dose and concentration of prilocaine is more suitable for regional intravenous anesthesia.